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Jinghai Zhang Selected Research

NSK-01105

3/2015NSK-01105 inhibits proliferation and induces apoptosis of prostate cancer cells by blocking the Raf/MEK/ERK and PI3K/Akt/mTOR signal pathways.
1/2014NSK-01105, a novel sorafenib derivative, inhibits human prostate tumor growth via suppression of VEGFR2/EGFR-mediated angiogenesis.

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Jinghai Zhang Research Topics

Disease

7Pain (Aches)
09/2022 - 05/2015
7Neoplasms (Cancer)
01/2022 - 12/2007
4Experimental Melanoma
08/2011 - 01/2007
3Infections
12/2017 - 11/2003
2Cardiac Arrhythmias (Arrythmia)
04/2021 - 11/2017
2Hepatocellular Carcinoma (Hepatoma)
01/2020 - 03/2016
2Porcine Reproductive and Respiratory Syndrome (PRRS)
01/2019 - 01/2018
2Cataract (Cataracts)
10/2004 - 07/2004
1Cardiovascular Diseases (Cardiovascular Disease)
09/2022
1Nervous System Diseases (Neurological Disorders)
07/2022
1Myocardial Infarction
04/2021
1Cardiac Sudden Death (Sudden Cardiac Arrest)
04/2021
1Atrial Fibrillation
04/2021
1Heart Failure
04/2021
1Poisoning
01/2021
1Septic Shock (Toxic Shock Syndrome)
01/2021
1Chronic Obstructive Pulmonary Disease (COPD)
01/2020
1Carcinogenesis
01/2020
1Neoplasm Metastasis (Metastasis)
01/2020
1Paralysis (Palsy)
11/2017
1Inflammation (Inflammations)
09/2015
1Prostatic Neoplasms (Prostate Cancer)
03/2015
1Colonic Neoplasms (Colon Cancer)
01/2009
1Colorectal Neoplasms (Colorectal Cancer)
01/2009
1Ataxia Telangiectasia (Louis Bar Syndrome)
01/2009
1Type 1 Spherocytosis
09/2008
1Microsatellite Instability
12/2007

Drug/Important Bio-Agent (IBA)

3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2020 - 01/2007
3Scorpion Venoms (Scorpion Venom)IBA
01/2018 - 05/2015
2GangliosidesIBA
07/2022 - 09/2015
2Formaldehyde (Formol)FDA Link
11/2021 - 04/2021
2Analgesics (Analgesic Drugs)IBA
11/2021 - 04/2021
2Voltage-Gated Sodium ChannelsIBA
01/2020 - 01/2018
2Pattern Recognition ReceptorsIBA
01/2019 - 01/2018
2NSK-01105IBA
03/2015 - 01/2014
2Messenger RNA (mRNA)IBA
08/2011 - 10/2004
2DNA (Deoxyribonucleic Acid)IBA
12/2007 - 12/2003
2Ophthalmic Solutions (Eye Drops)IBA
10/2004 - 07/2004
22-Hydroxypropyl-beta-cyclodextrinIBA
10/2004 - 07/2004
1dihydrosanguinarineIBA
09/2022
1dihydrochelerythrineIBA
09/2022
1Biomarkers (Surrogate Marker)IBA
01/2022
1Tumor Biomarkers (Tumor Markers)IBA
01/2022
1protopineIBA
11/2021
1tetrahydropalmatineIBA
11/2021
1corydalineIBA
11/2021
1dehydrocorydalinIBA
11/2021
1imperatorinIBA
04/2021
1isoimperatorinIBA
04/2021
1osthol (osthole)IBA
04/2021
1Ficusin (Psoralen)IBA
04/2021
1Methoxsalen (Oxsoralen)FDA Link
04/2021
1saikosaponin DIBA
04/2021
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
04/2021
1ExotoxinsIBA
01/2021
1staphylococcal enterotoxin BIBA
01/2021
1CytokinesIBA
01/2020
1Interleukin-6 (Interleukin 6)IBA
01/2020
1SmokeIBA
01/2020
1InterleukinsIBA
01/2020
1Opsonin Proteins (Opsonins)IBA
01/2019
1Protein Isoforms (Isoforms)IBA
01/2019
1Peptides (Polypeptides)IBA
01/2018
1peptidoglycan recognition proteinIBA
01/2018
1Apolipoproteins B (ApoB)IBA
12/2017
1apolipophorin IIIIBA
12/2017
1Sodium Channels (Sodium Channel)IBA
11/2017
1Fluorescent Dyes (Fluorescent Probes)IBA
06/2017
1Cell Adhesion MoleculesIBA
03/2016
1GD1a gangliosideIBA
09/2015
1Toll-Like Receptor 4IBA
09/2015
1Protein Kinases (Protein Kinase)IBA
09/2015
1MitogensIBA
09/2015
1Acetic Acid (Vinegar)FDA LinkGeneric
05/2015
1Therapeutic UsesIBA
03/2015
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
03/2015
1Sorafenib (BAY 43-9006)FDA Link
01/2014
1rho Guanine Nucleotide Dissociation Inhibitor betaIBA
08/2011
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
01/2011
1Antimicrobial PeptidesIBA
10/2010
1FlavonolsIBA
01/2009
1kaempferolIBA
01/2009
1Melanins (Melanin)IBA
09/2008
1Monophenol Monooxygenase (Tyrosinase)IBA
09/2008
1Enzyme Precursors (Zymogens)IBA
09/2008
1EnzymesIBA
09/2008
1pro-phenoloxidaseIBA
09/2008
1Complementary DNA (cDNA)IBA
05/2007
1Uridine Diphosphate (UDP)IBA
05/2007
1haematoside synthetaseIBA
05/2007
1Cytidine Monophosphate (CMP)IBA
05/2007
1Small Interfering RNA (siRNA)IBA
05/2007
1N-Acetyllactosamine SynthaseIBA
05/2007
1G(M3) GangliosideIBA
05/2007
1Glucosylceramides (Glucocerebrosides)IBA
05/2007

Therapy/Procedure

2Therapeutics
01/2022 - 01/2021
1Drug Therapy (Chemotherapy)
11/2021
1Immunotherapy
12/2018
1Analgesia
01/2018
1Surgical Instruments (Clip)
09/2008